Updating BLAST databases
There are two ways of updating the BLAST databases that come installed by default in the BLAST AMI:
1. Restart remote-fuser
Login to the instance and issue the following commands when there are no BLAST searches running on your instance:
/sbin/remote-fuser-ctl.pl --stop /sbin/remote-fuser-ctl.pl --start
This will discard the already downloaded BLAST databases and switch to the latest available BLAST databases from NCBI.